Medicinal Properties of Fenugreek: A Review

Varshney, Himanshi; Siddique, Yasir Hasan

Medicinal Properties of Fenugreek: A Review

Himanshi Varshney¹, Yasir Hasan Siddique^{1, *}

¹ Department of Zoology, Drosophila Transgenic Laboratory, Section of Genetics, Faculty of Life Sciences, Aligarh Muslim University, Aligarh 202002, Uttar Pradesh, India

Article Information

Identifiers and Pagination:

Year: 2023
Volume: 11
Publisher Id: e187503622302220
DOI: 10.2174/18741967-v11-e230327-2022-3

Article History:

Received Date: 02/08/2022
Revision Received Date: 23/01/2023
Acceptance Date: 08/02/2023
Electronic publication date: 31/03/2023
Collection year: 2023

© 2023 Varshney and Siddique

open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

^* Address correspondence to this author at the Department of Zoology, Drosophila Transgenic Laboratory, Section of Genetics, Faculty of Life Sciences, Aligarh Muslim University, Aligarh 202002, Uttar Pradesh, India; Tel: 0571-2700920-3447; E-mail:yasir_hasansiddique@rediffmail.com

Background:

Due to its numerous health benefits, fenugreek (Trigonella foenum-graecum L.) is commonly used in Ayurvedic and Traditional Chinese medicine. Its leaves and seeds contain several compounds (e.g., alkaloids, amino acids, coumarins, flavonoids, saponins, polyphenols, carbohydrates, vitamins, and other bioactive compounds). Fenugreek is used for reproductive health problems, hepatoprotective properties, and improved digestion. Studies have shown that it has anti-cancerous, cardioprotective, anti-sterility, antimicrobial, antiparasitic, anti-helminthic, and neuroprotective properties. Various studies have been carried out on animals and humans to show the effectiveness of fenugreek against various diseases.

Methods:

This review focuses on studies and clinical trials to examine the effects of fenugreek on various diseases from 1990 to 2022, using popular databases, such as Google Scholar, PubMed, and Scopus.

Results:

By altering the activity of metabolic enzymes, fenugreek stimulates insulin secretion, reduces blood sugar, and controls cholesterol synthesis. It enhances SOD, glutathione peroxidase, glutathione-S-transferase, and catalase activity to protect cellular organelles from oxidative stress. Fenugreek improves the gastric mucosa lining and secretion, which improves gastric ulcers and digestion. Fenugreek ameliorates menstrual cramps and significantly increases sperm cell counts and testosterone levels in males.

Conclusion:

Studies and clinical trials have shown the beneficial effects of fenugreek. Therefore, it could be used as a therapeutic agent against various disorders.

Keywords: Fenugreek, Medicinal properties, Diseases, Therapeutic agent, Pharmacology, Disorders.

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REVIEW ARTICLE

Medicinal Properties of Fenugreek: A Review

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