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The Open Biology Journal is an Open Access journal, which publishes research, review/mini-review and letter articles and guest edited single topic issues, reviews and letters in all areas of biology and at the interface of related disciplines. The core disciplines in biology that are published in the journal are the following: Cell & Developmental Biology; Genetics & Genomics; Molecular Biology; Structural Biology; Bioinformatics; Systems Biology; Immunology; Biochemistry; Ecology; Zoology; Ornithology; Entomology; Marine & aquatic Biology; Plant Biology; Bioethics; Behavioural science ; Microbiology; Reproductive Biology; Glycobiology; Macromolecules; Proteins & Peptides; Theoretical & Mathematical Biology; Evolutionary Biology; Techniques in Biology; Biotechnology, Applied Microbiology, Biodiversity Conservation, Biophysics, Biostatistics, Crystallography of macromolecules., education in biology, Marine & Freshwater Biology, Mathematical & Computational Biology, Mycology, Nanoscience & Nanotechnology, Parasitology, Paleobiology, Astrobiology; Physiology, biopolymers, Soil biology, and Interdisciplinary Applications in biology.

The Open Biology Journal, a peer-reviewed journal, is an important and reliable source of current information on developments in the field. Emphasis is placed on publishing quality papers, making them freely available to researchers worldwide.

Editor's Choice

Role of Genes and Treatments for Parkinson’s Disease

Falaq Naz, Yasir Hasan Siddique

Parkinson’s Disease (PD) is a complex neurodegenerative disorder that mainly results due to the loss of dopaminergic neurons in the substantia nigra of the midbrain. It is well known that dopamine is synthesized in substantia nigra and is transported to the striatum via nigrostriatal tract. Besides the sporadic forms of PD, there are also familial cases of PD and number of genes (both autosomal dominant as well as recessive) are responsible for PD. There is no permanent cure for PD and to date, L-dopa therapy is considered to be the best option besides having dopamine agonists. In the present review, we have described the genes responsible for PD, the role of dopamine, and treatment strategies adopted for controlling the progression of PD in humans.

October 15, 2020

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