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The Open Biology Journal is an open access online journal, which publishes research, review/mini-review and letter articles and guest edited single topic issues, reviews and letters in all areas of biology and at the interface of related disciplines. The core disciplines in biology that are published in the journal are the following: Cell & Developmental Biology; Genetics & Genomics; Molecular Biology; Structural Biology; Bioinformatics; Systems Biology; Immunology; Biochemistry; Ecology; Zoology; Ornithology; Entomology; Marine & aquatic Biology; Plant Biology; Bioethics; Behavioural science ; Microbiology; Reproductive Biology; Glycobiology; Macromolecules; Proteins & Peptides; Theoretical & Mathematical Biology; Evolutionary Biology; Techniques in Biology; Biotechnology, Applied Microbiology, Biodiversity Conservation, Biophysics, Biostatistics, Crystallography of macromolecules., education in biology, Marine & Freshwater Biology, Mathematical & Computational Biology, Mycology, Nanoscience & Nanotechnology, Parasitology, Paleobiology, Astrobiology; Physiology, biopolymers, Soil biology, and Interdisciplinary Applications in biology.


The Open Biology Journal, a peer-reviewed journal, is an important and reliable source of current information on developments in the field. The emphasis will be on publishing quality papers rapidly and freely available to researchers worldwide.


Recent Articles

The Presence of Microbial Air Contaminants in the Operating Theatre at a Teaching Hospital in East Coast Malaysia

Nor Azyan K.M. Khaidi, Siti M. Anua, Nurzafirah Mazlan, Safaa N. Saud

Aim:

The aim of this study is to determine the presence of microbial air contaminants in the operating theatre at a teaching hospital.

Objective:

Airborne microbial level in operation theatre is one of the significant risks in hospital as it can increase the surgical site infection and nosocomial infections.

Background:

Duo SAS Super 360 Air Sampler was used to collect the airborne samples in triplicate each for nutrient and MacConkey agar at eight operation rooms and two corridors for morning and evening sessions. Sampling was conducted for three months and repeated every two months. Microbiological culture, gram staining and biochemical tests such as catalase test, oxidase test, coagulase test, Triple Sugar Iron Agar test, urease test, citrate test, Sulfide, Indole, Motility test, Methyl Red Voges-Proskauer test, disc diffusion test, and Albert’s stain were performed on the pure isolated culture.

Methods:

Sampling was conducted for three months and repeated every two months. Microbiological culture, gram staining and biochemical tests such as catalase test, oxidase test, coagulase test, Triple Sugar Iron Agar test, urease test, citrate test, Sulfide, Indole, Motility test, Methyl Red Voges- Proskauer test, disc diffusion test, and Albert’s stain were performed on the pure isolated culture. Bacteria that were present in the operation rooms were Bacillus spp., Micrococcus spp. and Staphylococcus spp. while Pseudomonas aeruginosa and Acinetobacter baumannii were absent. The bacteria identified in the operation theater may also cause surgical site infections and nosocomial infections to the patients, although the microbial contamination in the air of the operation theatre is low.

Results:

The bacteria identified in the operation theater may also cause surgical site infections and nosocomial infections to the patients, although the microbial contamination in the air of the operation theatre is low.

Conclusion:

Strengthening surveillance on the hygienic condition of the operation theatre and routine sampling is strongly recommended to control all possible sources and types of infection.


February 16, 2021
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Editor's Choice

Role of Genes and Treatments for Parkinson’s Disease

Falaq Naz, Yasir Hasan Siddique

Parkinson’s Disease (PD) is a complex neurodegenerative disorder that mainly results due to the loss of dopaminergic neurons in the substantia nigra of the midbrain. It is well known that dopamine is synthesized in substantia nigra and is transported to the striatum via nigrostriatal tract. Besides the sporadic forms of PD, there are also familial cases of PD and number of genes (both autosomal dominant as well as recessive) are responsible for PD. There is no permanent cure for PD and to date, L-dopa therapy is considered to be the best option besides having dopamine agonists. In the present review, we have described the genes responsible for PD, the role of dopamine, and treatment strategies adopted for controlling the progression of PD in humans.


October 15, 2020
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