Aims and Scope

The Open Biology Journal is an open access online journal, which publishes research, review/mini-review and letter articles and guest edited single topic issues, reviews and letters in all areas of biology and at the interface of related disciplines. The core disciplines in biology that are published in the journal are the following: Cell & Developmental Biology; Genetics & Genomics; Molecular Biology; Structural Biology; Bioinformatics; Systems Biology; Immunology; Biochemistry; Ecology; Zoology; Ornithology; Entomology; Marine & aquatic Biology; Plant Biology; Bioethics; Behavioural science ; Microbiology; Reproductive Biology; Glycobiology; Macromolecules; Proteins & Peptides; Theoretical & Mathematical Biology; Evolutionary Biology; Techniques in Biology; Biotechnology, Applied Microbiology, Biodiversity Conservation, Biophysics, Biostatistics, Crystallography of macromolecules., education in biology, Marine & Freshwater Biology, Mathematical & Computational Biology, Mycology, Nanoscience & Nanotechnology, Parasitology, Paleobiology, Astrobiology; Physiology, biopolymers, Soil biology, and Interdisciplinary Applications in biology.

The Open Biology Journal, a peer-reviewed journal, is an important and reliable source of current information on developments in the field. The emphasis will be on publishing quality papers rapidly and freely available to researchers worldwide.

Recent Articles

Genetic Diversity of Two Tilapia Species (Oreochromis Niloticus and Sarthrodon Galilaeus) Using Random Amplified Polymorphic DNA

Omeima M. Omer, Abd El Wahab H. Abdalla, Zuheir N. Mahmoud


In this study, the genetic variability in eight populations of Oreochromis niloticus and seven populations of Sarotherodon galilaeus was estimated using molecular markers.

Materials and Methods:

Fish specimens were collected from eight sites representing the White Nile, Blue Nile and the River Nile. Tissue samples from gills and dorsal fin were removed from individual specimens and preserved separately in absolute ethanol prior to molecular analysis by RAPD-PCR using eight primers. DNA analysis using OPA-04, OPA-13, OPA-03, OPA-06, OPA-07, OPA-09, OPA-10 and RAPD-8 produced different bands for each.

Results and Discussion:

The total bands generated by the primers were: 17, 16, 18, 12, 12, 14, 14, and 17. They were in the range of 100 to 1020 bp. Levels of variability were estimated by the proportion of polymorphic bands obtained by each primer within a population. The range of variability was wider in O. niloticus (46.0 to 91.7) compared to S. galilaeus (56.2 to 83.3). The dendrogram obtained differentiated the populations into 22 sub-clusters. Oreochromis niloticus from Al Kalakla exhibited a high level of genetic diversity. This diversity is evident among and within the studied populations, as estimated by RAPD-PCR techniques.


To promote tilapia production, the study recommended increasing genetic variation within broodstocks by crossing high similarity breeds with low similarity ones.

September 25, 2020

Editor's Choice

Safety of Using Diapers Containing Copper Oxide in Chronic Care Elderly Patients

Weinberg I, Lazary A, Jefidoff A, Vatine J-J, Borkow G, Ohana N

Copper has very potent antibacterial, antifungal, antiviral and acaricidal properties. Recently the use of copper alloys in hospital wards has been shown to reduce bioburden and nosocomial infection rates. We hypothesized that the use of copper oxide in textiles and other products that are in close contact with the patients may significantly reduce bioburden in clinical settings and consequently reduce the risk of nosocomial infections. In order to test this hypothesis we intend to conduct a trial in which we will examine if the nosocomial infection rates in a chronic care ward will be reduced when all the textile products will include copper oxide. The risk of adverse reactions due to dermal contact with copper are considered extremely low and medical devices containing copper, such as intrauterine devices and dental amalgams, are safely used for decades. Textile products containing copper oxide are being sold worldwide for several years and not even one adverse reaction was noted. However, in spite of all the above, and in preparation to the clinical trial we intend to conduct in a chronic care ward (long-term care facility), we conducted this preliminary study in which we examined the safety of using copper oxide impregnated diapers in 16 chronic care patients that used the diapers for 6 consecutive months. Importantly, not even one adverse reaction was recorded during the whole trial, indicating the high safety of the diapers. Therefore, this study allows us to examine the efficacy of textiles containing copper oxide in reducing nosocomial infections in larger populations, including in frail chronic care patients.

February 22, 2013

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